title:: US8224640B2 — Method and system for computational modeling of the aorta and heart
patent:: US8224640B2
status:: granted 2012-07-17 · Active
filed:: 2010-06-29
assignee:: Siemens AG
people:: Puneet Sharma, Bogdan Georgescu, Razvan Ioan Ionasec, Dorin Comaniciu
domain:: Biomechanics, Computational Modeling, Computational Fluid Dynamics, Cardiology
link:: https://patents.google.com/patent/US8224640B2/en
Figure 1 from the published patent document. Patent drawings are public records.
Why this one
The patent behind the simulation line of the research — geometry, mechanics and flow in one personalised pipeline, and the claim structure of the whole cardiac-modelling programme.
Abstract
A method and system for generating a patient specific anatomical heart model is disclosed. A sequence of volumetric image data, such as computed tomography (CT), echocardiography, or magnetic resonance (MR) image data of a patient’s cardiac region is received. A multi-component patient specific 4D geometric model of the heart and aorta estimated from the sequence of volumetric cardiac imaging data. A patient specific 4D computational model based on one or more of personalized geometry, material properties, fluid boundary conditions, and flow velocity measurements in the 4D geometric model is generated. Patient specific material properties of the aortic wall are estimated using the 4D geometrical model and the 4D computational model. Fluid Structure Interaction (FSI) simulations are performed using the 4D computational model and estimated material properties of the aortic wall, and patient specific clinical parameters are extracted based on the FSI simulations. Disease progression modeling and risk stratification are performed based on the patient specific clinical parameters.
Data Points
- US8224640B2 — granted US patent (kind code B2)
- Filed 2010-06-29, granted 2012-07-17
- Legal status today — Active
- Assignee — Siemens AG
- Co-inventors — Puneet Sharma, Bogdan Georgescu, Dorin Comaniciu
Part of the complete record in Patents.
